The purpose of the study is to evaluate the physical performance of a Biograph mCT Flow R PET/CT system (Siemens Healthcare, Germany) and to. to fundamentally change how PET imaging is performed. Powered by Siemens’ revolutionary FlowMotion™ technology,. Biograph mCT Flow™ is the world’s first. Biograph mCT Flow with FlowMotion™ technology combines our standard- setting PET/CT with a unique system design that enables continuous motion of.

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For the measurements for the sensitivity, the count rate performance, and the associated relative count rate error, a provision was made in NEMA NU for elevating the phantoms, if the vertical range of the patient table is insufficient for the required placement of the phantoms.

National Electical Manufacturers Association. Online random subtraction was applied from a delayed coincidence window. The extra bed position information is then employed during the data processing, thus, assuring that the final reconstructed images contain the correct position information.

Dynamic whole body PET parametric imaging: The calculated activities at the start of the second scan were 5. For an axial FOV excluding the low sensitivity regions at the axial endpoints mvt the scan range a hypothetical scan with an unlimited number of bed positionsa 4-min acquisition per bed position corresponds to a table speed of 0.

The elevated background variability is assumed to be caused by the choice of the table speed and the data processing techniques specific to CTM acquisitions. The sphere-to-background ratio is 8: Bipgraph, this study was performed on a different system with an axial FOV of Conclusions The spatial resolution, sensitivity, scatter fraction, and count rates were biogdaph concordance with the published values for the predecessor system, the Biograph mCT. Seminars in Nuclear Medicine.

No noticeable difference between the two systems was observed. This is the result of the low sensitivity in this part of the axial FOV Fig. These artifacts can be reduced by applying post-filtering with small to modest amounts of blurring but at the cost of lower image contrast. For this evaluation, the measurements acquired for the evaluation of the scatter fraction and count rate performance was used. This information can be used to significantly improve the image signal-to-noise ratio SNR of the reconstructed PET images, thus, allowing for better image quality and shorter acquisition times [ 89 ].


Table 3 Image quality results for 4: A second scan of the same region in CTM mode was acquired at a table speed of 0. The scatter fraction and NECR were determined as described in the NEMA NU standard [ 19 ] acquired using software tools provided by the manufacturer and evaluated using in-house software.

Biograph mCT 20 Excel

At the start of the first measurement, the activity of the point source was 0. The changes in bladder filling are caused by the time between the scans. A similar increase was observed in the CVs which equate to the background variability in the bladder of the two patients.

Ethical approval All mtc performed in studies involving human participants were approved by the regional ethics committee and were in accordance with the Helsinki declaration. In a study by Tong et al. A digital architecture biogrwph routinely storing and buffering the entire bit event stream at maximum bandwidth for every acquisition in clinical blograph 3-D PET: Contributor Information Ivo Rausch, Phone: The CRCs were similar in both acquisition modes.

Impact of point spread function modelling and time of flight on FDG uptake measurements in lung lesions using alternative filtering strategies.

Biograph mCT

The axial sensitivity profiles with the line source placed at the center of the FOV and cm radial offset are shown in Fig. Based on the results of Armstrong [ 25 ], this difference would increase for the smaller spheres when TOF was included into the reconstruction algorithm. Nevertheless, enhanced noise at the axial edges in the SS mode acquisition was observed. This configuration provides an axial field-of-view FOV of The CTM scans were acquired with a table speed of 1.

Healthcare Siemens White Paper. Nevertheless, CTM enables the use of varying table speeds for different axial regions. National Electrical Manufacturers Association. The phantom was positioned with all spheres aligned within the same transaxial image plane in the center of the FOV.


Biograph mCT for Radiation Oncology – Siemens Healthineers Global

Sensitivity measurements were based on a cm-long polyethylene tube, filled with 4. The background variability was between 2. Nonetheless, increased noise was observed viograph the images acquired in SS mode Fig.

Nevertheless, the choice of the reconstruction parameters in our study for the evaluation of the image quality was based on the NEMA NU2 standard that asks to use clinically relevant settings.

No attenuation and scatter correction and biogrpah post-smoothing filter were applied.

Biograph mCT Flow – Siemens Healthineers USA

Footnotes Competing interests The authors declare that they have no competing interests. This set of parameters should be defined by biograh vendor and be delivered with the system, e. Regarding the IQ test, the only difference between the and standard is a reduction of emission scan time by a factor of 2.

The mCT Flow system had a sensitivity of 9.

While the difference in error may be small, the exclusion of the end slices as permitted in the NEMA NU protocol should be followed anyway, as these end slices often suffer from high noise levels due to the low sensitivity of the scanner at the end of the axial FOV Fig. The bladder was chosen to test for this issue as it contains a uniform activity concentration and therefore similar to the background compartment in the IQ phantom.

The system bkograph was then computed as the ratio between the true count rate with no absorption and the starting activity. The acquisition electronics is based on solid-state components capable of continuously recording and storing detector addresses. All data were corrected for random coincidences, normalization, dead time losses, scatter, and attenuation.

Therefore, the CTM acquisitions resulted in a lower number of collected true events than in SS mode, which in turn resulted in an elevated mtc variability [ 33 ].

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